Research and Progress

Antiretroviral drug used to prevent HIV or hepatitis B shows promise for Alzheimer’s disease treatment in early clinical trials

August 7, 2024

A pilot study led by scientists from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) shows promise for people with mild cognitive changes treated with lamivudine, a Food and Drug Administration-approved antiretroviral drug. The study reveals significant improvement in neurodegeneration and inflammation. Lamivudine is an antiviral medicine that prevents […]


Antiretroviral drug shows potential for Alzheimer’s disease treatment in early clinical trials

July 31, 2024

Scientists from The University of Texas Health Science Center at San Antonio, also known as UT Health San Antonio, led a pilot study of the Food and Drug Administration-approved antiretroviral drug lamivudine, to determine if it could be a potential treatment for Alzheimer’s disease. Almost half of what makes up the human genome are mysterious […]


Fastest-rising U.S. institutions for research output – UT Health Science Center San Antonio ranks 6th in top 10 nationally

July 2, 2024

The University of Texas Health Science Center at San Antonio has been rated No. 6 on the top 10 list of fastest-rising United States institutions for research output ranked by Nature Index in May 2024. The UT Health Science Center San Antonio outpaced in biological sciences research output with a 52.6% increase in adjusted research output share from […]


Research finds causal evidence tying cerebral small-vessel disease to Alzheimer’s, dementia

June 21, 2024

Research led by in part by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) finds that the most common cerebral small-vessel disease feature seen in brain magnetic resonance imaging is a primary vascular factor associated with dementia risk. Results of the major international study emphasize the significance of that […]


San Antonio Express News: UT Health San Antonio plans $100 million research tower to focus on cancer, aging, diabetes, obesity

June 11, 2024

UT Health San Antonio to build a $100 million science tower to further advance research on cancer, aging, brain disease, diabetes and obesity. Read the article at ExpressNews.com.



Construction of Center for Brain Health more than a third complete

April 19, 2024

Construction on the $100 million Center for Brain Health, a new patient care and clinical trials facility of UT Health San Antonio, is now about 35% complete, with full completion expected by September 2025 and an anticipated opening in December 2025. The Center for Brain Health — located at 4940 Charles Katz Drive — is […]




Texas Public Radio: Fighting Alzheimer’s at the eye doctor

April 2, 2024

Margaret Flanagan, MD, is a neuropathologist at the Biggs Institute — an expert in brain tissue and how it changes in the presence of diseases like Alzheimer’s. Dr. Flanagan is working on a test to help detect dementia early at the eye doctor’s office. Listen here to learn more: Science & Medicine: Fighting Alzheimer’s at the […]




Studying a vaccine for Alzheimer’s disease in those with Down syndrome

March 21, 2024

  How the connection of Down syndrome and Alzheimer’s disease could be the start to a vaccine against Alzheimer’s. Significant levels of amyloid beta plaques and tau tangles in the brain are classic hallmarks of Alzheimer’s disease. These precursors are also prevalent in the understudied population of those with Down syndrome. Although nearly all people […]



KSAT: Brain thinning could predict dementia 5 to 10 years before symptoms, local study shows

January 30, 2024

Through a decade’s worth of findings, researchers at the Biggs Institute for Alzheimer’s and Neurodegenerative Diseases at UT Health San Antonio are discovering a connection between the thickness of brain tissue to dementia risks. Claudia Satizabal, PhD, associate professor at the Biggs Institute and lead researcher on this study, said duplicating this marker could be […]


$32 million NIA grant boosts long COVID cognition study of under-studied populations including South Texas Hispanics

December 14, 2023

COVID-19’s long-term effects on cognition in older adults will be studied for five years thanks to a $32 million federal grant awarded to The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio). The National Institute on Aging (NIA) grant, with UT Health San Antonio as the coordinating center, […]