Research

Dozens more genes linked with stroke; potential drug targets identified

September 28, 2022

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) are part of an international team that discovered 61 additional genetic loci associated with stroke and six genes that are potential targets for drug therapy to prevent or treat stroke. The findings, published today (Sept. 28) in Nature, are […]


Alzheimer’s Weekly: Success in Delaying Dementia

August 15, 2022

Sudha Seshadri, MD, professor of neurology and founding director of the Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases at UT Health San Antonio, discusses her latest research surrounding the trend of people developing dementia later in life and the relation to strokes. To read the article, visit AlzheimersWeekly.com.


Scientists hope to create a health ‘scorecard’ for dementia risk

July 5, 2022

    UT Health San Antonio is site for a new major study of diverse communities is looking at how brain changes and genetics contribute to dementia and Alzheimer’s. UT Health San Antonio is a clinical research site for a new study, Diverse Vascular Contributions to Cognitive Impairment and Dementia, or Diverse VCID. by UC […]



Novel brain injury treatment tested in 1st human subject

June 15, 2022

An experimental brain injury medication conceived in laboratories at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) was tested Tuesday, June 14, in the first human subject, a clinical trial participant in Hungary. If the drug, called AST-004, performs well in human studies, it will be an urgently needed […]




San Antonio Express News: UTSA awards $4 million to Alzheimer’s researchers around the world

June 9, 2022

Bess Frost, PhD, Bartell Zachry Distinguished Professor for Research in Neurodegenerative Disorders at the Biggs Institute for Alzheimer’s and Neurodegenerative Disorders at UT Health San Antonio, has been awarded $500,000 to advance her studies on the causes of Alzheimer’s disease. Frost is currently enrolling patients with a diagnosis of early Alzheimer’s for a trial studying […]




Rapamycin increases Alzheimer’s-associated plaques in mice, study finds

June 7, 2022

The research also reveals a novel way to decrease the plaques. This is a potential drug target. Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer’s disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid […]




NIA: Senescent brain cells may contribute to Alzheimer’s disease

May 26, 2022

New research shows senescent brain cells, damaged cells that do not die off, are found more in Alzheimer’s disease than in people without the disease. The study was led by researchers at NIA-supported Alzheimer’s Disease Research Centers at the Wake Forest University School of Medicine and the Biggs Institute at the University of Texas Health […]



Med Page Today: Brain Aging Markers Tied to Inflammatory Foods

May 16, 2022

New research is revealing how high inflammatory foods are connected brain aging markers and cerebral small vessel disease. Debora Melo van Lent, PhD, a postdoctoral researcher at the Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, speaks to this research of a high inflammatory diet. To read the article, visit MedPageToday.com.



In the race to solve Alzheimer’s disease, scientists find more needles in the haystack

April 20, 2022

21 million. That’s the number of genetic variations in the human genome that researchers are sifting to identify patterns predisposing people to Alzheimer’s disease. Thanks to international collaboration, more genetic variations for Alzheimer’s disease are known today than ever before. The list of gene variants recognized for late-onset Alzheimer’s grew from one in 2009 to […]



In the quest for a TBI therapy, astrocytes may be the bull’s-eye

February 11, 2022

Growing evidence suggests that traumatic brain injury (TBI) is an important risk factor for developing Alzheimer’s disease and dementia. But to date, effective therapies aren’t available for preventing or treating TBI-induced disease. Scientists may be on to something, though. New studies from The University of Texas Health Science Center at San Antonio (UT Health San Antonio), published […]