Research


Stroke bleeds in the brain not decreasing, study finds

June 9, 2020

Brain bleeds called intracerebral hemorrhages remained stable in incidence among all age groups over the past 30 years, but they increased in people 75 and older, according to a new analysis of the Framingham Heart Study. The findings are in JAMA Neurology. Use of anticoagulants also increased in senior adults threefold over the period, but authors cautioned against […]



Medical Xpress: Cognition and gait speed often decline together, study shows

May 7, 2020

Do thinking and walking go hand in hand in determining the health course of senior adults? A study published by UT Health San Antonio researchers found that, indeed, the two functions often parallel each other in determining a person’s health trajectory. The researchers analyzed data from 370 participants in the San Antonio Longitudinal Study of […]


‘Reasons for Hope’ summarizes dementia advances, encourages 300

February 28, 2020

“No matter how long it takes, no matter how much it costs, UT Health and I are in this fight until we win. This disease motivates us to expend our maximum energy at every moment, because there is so much at stake and there are so many depending on us.” With those words, William Henrich, […]


Biggs Institute joins NIH network studying post-stroke dementia

February 25, 2020

UT Health San Antonio is part of a National Institutes of Health (NIH) stroke research network announced Feb. 19 at the International Stroke Conference in Los Angeles. Sudha Seshadri, M.D., professor of neurology and founding director of the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, is serving on the Steering Committee as co-leader of […]


Inflammatory marker linked to dementia

December 12, 2019

An inflammatory marker called sCD14 is related to brain atrophy, cognitive decline and dementia, according to a study of more than 4,700 participants from two large community-based heart studies. The study was published Dec. 9 in the journal Neurology. “We have strong reason to believe that sCD14 can be a useful biomarker to assess a person’s […]


Medical Xpress: Rapamycin prevents age-related brain vascular deterioration

November 7, 2019

Featured in Medical Xpress A just-released study by UT Health San Antonio and collaborating institutions shows age-related decreases in blood flow to the brain and memory loss can be modified with the drug rapamycin. This finding, if furthered, holds implications for aging in general and perhaps offers an avenue to prevent Alzheimer’s dementia in some […]


Biggs Institute seeks 10 volunteers for study of Alzheimer’s drug

October 23, 2019

The Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases at UT Health San Antonio is recruiting volunteers for a clinical study of an investigational drug for Alzheimer’s disease. The principal investigator for this study is Sudha Seshadri, M.D., professor of neurology at UT Health San Antonio and director of the Glenn Biggs Institute. The Biggs […]


Gene variants influence size of brain stem, other structures

October 21, 2019

Global research project suggests novel drug targets for brain diseases Researchers have found a link between 48 common genetic variations and the size of the brainstem and other subcortical structures deep within the brain. These structures control a wide array of functions ranging from learning and fear response to heart rate and voluntary movement. Damage […]


Neurology Today: Elevated plasma tau predicts stroke risk over and above other factors

August 8, 2019

By Richard Robinson ARTICLE IN BRIEF:In blood samples from participants in the longitudinal Framingham Heart Study, researchers applied a highly sensitive test for total tau and found that those with higher levels had an increased risk for stroke. Elevation of tau in the bloodstream is an independent risk factor for stroke, according to a study […]


Largest study of CTE finds it in 6% of subjects

June 21, 2019

Nearly 6% of athletes and non-athletes were found to have the neurodegenerative disorder chronic traumatic encephalopathy (CTE) in the largest, and broadest, study conducted of the disease to date. The findings were published June 14 in the international journal Brain Pathology. “Generally our findings point to CTE being more common in athletes and more common in football […]