South Texas Alzheimer's Conference
February 25-26, 2019 at the Wyndham Garden San Antonio Riverwalk Hotel
All health care professionals and students interested in collaboration and discussion on transformational care, research and therapeutics in Alzheimer’s disease are invited to the inaugural South Texas Alzheimer’s Conference.
Event schedule
Day 1
Welcome and Opening Remarks
- William L. Henrich, M.D., FACP
- Maria Carrillo, Ph.D.
- Sudha Seshadri, M.D.
- Gladys E. Maestre, M.D., Ph.D.
Chair: Maria Carrillo, Ph.D.
- “Cognitive Aging, Decline and Impairment Among Diverse Latinos in the Study of Latinos—
Investigation of Neurocognitive Aging,” Hector M. González, Ph.D. - “Differences in the Biology of Cognitive Impairment Within a Diverse Cohort,” Charles DeCarli, M.D.
Prediction and Prevention of Dementia: Focus on Hispanic Populations
Chairs: Lenore J. Launer, Ph.D., M.Sc., and Donald Royall, M.D.
- “Alzheimer’s at the South Texas Border,” Gladys E. Maestre, M.D., Ph.D.
- “Precision Medicine for Neurodegenerative Disease Among Mexican Americans,” Sid E. O’Bryant, Ph.D.
- “A Colombian Thousand Genomes Project for Early-Onset Dementia,” Kenneth S. Kosik, M.D., M.A.
- “The Memento Cohort: New Insights on Alzheimer’s Disease and Related Causes of Dementia Prediction Modeling,” Carole Dufouil, Ph.D.
- “Genetic Approaches to Risk of Dementia in Mexican Americans,” John Blangero, Ph.D.
Featured Presentations of the Biggs Institute
- “Population-Based Research in Mexican Americans,” Claudia L. Satizabal, Ph.D.
- “Sensory-Motor Dysfunction: A Window of Opportunity for Pre-Clinical Detection of Alzheimer’s Disease,” Mini E. Jacob, M.D., Ph.D.
- “Computational Biology at the Biggs Institute,” Habil Zare, Ph.D.
Roundtable I: Brain Health in the Hispanic Population
Chair: Sudha Seshadri, M.D.
- Maria Carrillo, Ph.D.
- Gladys E. Maestre, M.D., Ph.D.
- Hector F. Gonzalez, M.D., M.P.H.
- John Blangero, Ph.D.
- Sarah Williams-Blangero, Ph.D.
- Mary Ellen Quiceno, M.D., FAAN
- Gabriel A. de Erausquin, M.D., Ph.D., M.Sc.
Comprehensive Care in Neurodegenerative Diseases
Chairs: Carlos Roberto Jaén, M.D., Ph.D., M.S., and Rita Hortenstine
- “Making a Difference: Patient and Caregiver Engagement,” Lisa M. Shulman, M.D.
- “When Words Fail: Restitutive Interventions for Communication in Progressive Aphasia,” Maya Henry, Ph.D.
- “Texas Alzheimer’s Research and Care Consortium,” Munro Cullum, Ph.D.
- “Caregiving Resources,” Ginny Funk
Featured Presentations of the Biggs Institute
- “Memory Clinic,” Alicia Parker, M.D.
- “Biggs Institute Neuropsychology,” A. Campbell Sullivan, Psy.D., ABPP-CN
- “The Biggs Institute Brain Bank: Comprehensive Care and Closure,” Kevin F. Bieniek, Ph.D.
- “Supportive Care 101,” Neela K. Patel, M.D., M.P.H., CMD
- “Comprehensive Care for Family Caregivers: The Caring for the Caregiver Program,” Carole White, Ph.D., R.N.
- “Responding to Elder Abuse and Neglect in Caregiving,” Carolyn E.Z. Pickering, Ph.D., R.N.
Day 2
Plenary Session III
Chairs: Robin Brey, M.D. and Gladys E. Maestre, M.D., Ph.D.
- “Alzheimer’s Disease Diagnosis 2019: Research or Clinical?” Ronald C. Petersen, M.D., Ph.D.
- “A Precision Medicine Approach to Complex Common Diseases,” Eric Boerwinkle, Ph.D.
- “Precision, Personalized Approaches to Alzheimer’s Disease and Related Dementias: Are We on the Horizon of a ‘Cure?’” Sudha Seshadri, M.D.
Novel Therapeutic Paradigms and Biomarkers
Chairs: Robert A. Clark, M.D., MACP, and Nicolas Musi, M.D.
- “Biomarkers of Cerebral Small Vessel Disease,” Fanny Elahi, M.D., Ph.D.
- “DLK Inhibitors as Novel Therapeutics for Neurodegenerative Diseases,” William J. Ray, Ph.D.
- “Therapeutic Antibodies Targeting Toxic Oligomers in Neurodegenerative Diseases,” Rakez Kayed, Ph.D.
- “Inducing Cognitive Resilience as a Novel Therapeutic Approach to AD,” Giulio Taglialatela, Ph.D.
- “The Role of Autophagy in Neurodegeneration,” Mathieu Bourdenx, Ph.D.
Featured Presentations of the Biggs Institute
- “Disruption of Nuclear Architecture in Neurodegenerative Tauopathy,” Bess Frost, Ph.D.
- “Tau Induced Cellular Senescence is a Treatable Source of Neuroinflammation and Neurodegeneration,” Miranda Orr, Ph.D.
- “Mechanisms of Brain Vascular Dysfunction in Alzheimer’s Disease,” Veronica Galvan, Ph.D.
Precision Medicine, Genomics and Neuroimaging Part I
Chairs: George Perry, Ph.D., and Marilyn Miller, Ph.D.
- “Deep Diving into Mendelian Neurological Developmental Disorders,” Richard A. Gibbs, AC Ph.D.
- “Precision Medicine to Identify High-Risk Individuals: Are We There Yet?,” M. Arfan Ikram, M.D., Ph.D., M.Sc.
- “Development and Validation of Resting-State fMRI Biomarkers for Age-Related Cognitive Disorders,” Peter T. Fox, M.D.
- “Precision Disease Modeling Using Human iPSCs and 3D Organoids,” Jenny Hsieh, Ph.D.
- “Functional Genomics of Alzheimer’s Disease,” Joshua M. Shulman, M.D., Ph.D.
Precision Medicine, Cognitive Phenotypes, Genomics and Neuroimaging Part II
Chairs: Lenore J. Launer, Ph.D., M.Sc., and Paul E. Schulz, M.D.
- “Identification of Genetic Modifiers in High-Risk Cohorts: PSEN1 Mutation Carrier Families and Adults with Down Syndrome,” Joseph H. Lee, Dr.P.H.
- “To the Crux of the Matter: Molecular Determinants of Cerebral Small Vessel Disease,” Myriam Fornage, Ph.D.
- “How Neuropsychology Does (and Doesn’t) Contribute to Precision Phenotyping and Differential Diagnosis,” Joel Kramer, Psy.D.
- “Searching for the Genetic Roots of Successful Brain Aging,” David Glahn, Ph.D.
- “PET: A Window on Molecular Events in Alzheimer’s,” Joseph C. Masdeu, M.D., Ph.D.
- “Fundació ACE Research in Alzheimer’s Disease: Intramural Programs, Nationwide Efforts and International Alliances,” Agustín Ruiz, M.D., Ph.D.
Roundtable II: Connecting the Dots—Framework for Connecting Datasets and Research Globally
Chairs: Sudha Seshadri, M.D., and Marilyn Miller, Ph.D.
- George Perry, Ph.D.
- Richard A. Gibbs, AC Ph.D.
- Eric Boerwinkle, Ph.D.
- Jenny Hsieh, Ph.D.
- Carole Dufouil, Ph.D.
- M. Arfan Ikram, M.D., Ph.D.
- Byron C. Hepburn, M.D.,
- Maj. Gen. (USAF Ret.)
- Agustín Ruiz, M.D., Ph.D.
