Sudha Seshadri, MD

Director of the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases

Personal Statement:

Sudha Seshadri, MD, is a behavioral neurologist and the Robert R. Barker Distinguished University Professor of Neurology, Psychiatry and Cellular and Integrative Physiology at the Joe R. and Teresa Lozano Long School of Medicine at the University of Texas Health Sciences Center at San Antonio. Since December 2017, she has served as the founding director of the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases which was awarded a National Institute on Aging designated Alzheimer’s Disease Research Center in 2021. The Biggs Institute combines comprehensive, compassionate, continuing clinical care for a broad range of vascular and neurodegenerative diseases with basic, computational and epidemiological research, community outreach, advocacy, training and education. The institute has a special emphasis on bringing the most advanced precision prevention, diagnosis and treatment approaches to the underserved Hispanic communities in South Texas.

Dr. Seshadri completed her medical education and residency training in Internal Medicine and Neurology at the Christian Medical College, Vellore, the Madras Medical College, Chennai and at the All India Institute of Medical Sciences in New Delhi. She later completed a second residency at Boston University, along with fellowship training in the Neurobiology of Aging and in Neuroepidemiology at the University of Massachusetts Medical Center in Worcester, Massachusetts and the National Heart, Lung, and Blood Institute Framingham Heart Study where she remains a senior investigator, with an adjunct appointment as professor of neurology at Boston University.

Her research interests are in uncovering the biology of Alzheimer’s and related dementias, stroke and vascular brain injury through epidemiological, genetic, multi-omic and biomarker studies on large, population-based cohorts. In parallel, she continues to see patients and lead clinical trials of promising therapies. She has over $95 million in grant funding from the National Institutes on Health (NIH), over 500 peer-reviewed publications, mentored over 45 physicians and scientists and won awards as a teacher, clinician and researcher, including election to Alpha Omega Alpha and the Association of American Physicians. Dr. Seshadri has lectured extensively, nationally and internationally and leads several national and international consortia. She is a recognized thought leader in Alzheimer’s and has been featured over 150 times in public media. Her goal is to leave a legacy of some effective preventive or therapeutic interventions for dementia, and a cadre of dedicated and caring clinicians and scientists whom she has helped empower.

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Medical School:
Madras Medical College, University of Madras

Boston University School of Medicine

Saint Vincent Hospital - Worcester
Boston University School of Medicine


The New York Times: Prolonged Sleep may be Early Warning Sign of Dementia

Sudha Seshadri, MD, comments on the link between sleep and early cognitive decline.

TIME Magazine: Stressed-Out People May Have Smaller Brains, Study Says

Study co-author, Sudha Seshadri, MD, comments on how the effects from stress could be a precursor to cognitive decline later in life.

CNN: Genetic predisposition toward higher blood pressure, cholesterol may be linked to Alzheimer’s risk, study finds

Sudha Seshadri, MD, was interviewed by CNN on a research study showing certain forms of higher blood pressure and cholesterol with a genetic link could be related to an increased risk of developing Alzheimer’s disease.