Clinical Researchers
Tiffany F. Kautz, PhD
Research focuses upon identifying biomarkers for earlier identification of Alzheimer’s disease and related neurodegenerative diseases. Actively involved in coordinating research collaborations to further these research interests, including the Markers for Vascular Contributions to Cognitive Impairment and Dementia (MarkVCID) and Cognitively Healthy Nonagenarians in the Cross Cohort Collaboration (CCC). Also serves as the creator and coordinator of the Biggs Biobank, a comprehensive repository of biofluids and tissues from a variety of neurodegenerative disorders as well as cognitively healthy controls.
Research Areas
Clinical Research
Mini E. Jacob, MD, PhD
Research focuses on the process of disablement among older adults, particularly on the intertwining pathways to mobility disability and dementia. Previous studies evaluated whether behavioral factors like diet and physical activity in early old age can continue to influence health and affect the length of terminal morbidity and disability. Ongoing projects examine patterns and burden of multi-morbidity as a risk factor for disablement, the role of cognitive impairment in the pathway to disability and how a combination of physical and cognitive impairment can influence disablement. Current objectives also include evaluating how physical function measures correlate with markers of Alzheimer’s disease in asymptomatic individuals and identifying mobility measures that reflect brain vascular pathology.
Research Areas
Clinical Research, Population Neuroscience
Sarah Horn, MD
Sarah Horn, MD, is a movement disorders specialist with expertise in the diagnosis and management of Parkinson’s disease and related neurodegenerative parkinsonian disorders. Dr. Horn has an interest in comparative effectiveness research and clinical trials and is currently the principal investigator for an actively enrolling pragmatic clinical trial funded by the Alzheimer’s Association studying the long-term effects of quetiapine versus pimavanserin for psychosis associated with Parkinson’s disease and dementia with Lewy bodies in a real-world setting.
Research Areas
Clinical Research