Some of the most exciting advances and discoveries in dementia research come from studying brain tissue, which is why we need your help.

Families receive a definitive diagnosis

Details of the donor’s medical history are collected and a careful examination of the donation is performed. A neuropathology report will then be sent to families on the type and levels of pathology found, helping family members assess their risks for developing dementia or other neurological diseases.

Everyone can donate

People who do not exhibit memory loss or other cognitive problems can also choose brain donation to help advance research. Brains without disease help us determine which changes in the brain are from normal aging and what makes some individuals resistant to diseases like Alzheimer’s. No referrals are needed to donate.

Free donation arrangements

There is no financial expense to donate and donating does not delay funeral arrangements. Working with the donor’s family, the Biggs Institute will coordinate all necessary arrangements for transportation and donation.

Brain donation is a decision that should be discussed with family members. We are here to help you with these conversations. For more information, contact us at 210-450-8423 or

Enroll in 3 easy steps!

Click here to learn how to enroll or complete the enrollment forms.

Frequently asked questions

View frequently asked questions about brain donation.

For questions or to enroll:

Contact 210-450-8423 or

When the time comes to donate, call our 24/7 donation phone number:


Answers for families and research

Read featured stories on how our nationally recognized Brain Bank is leading the discovery in dementia research.

Banking on the Brain

Currently, the best method for understanding the changes in our brain that cause dementia symptoms is a brain autopsy.

Learn why the state’s only designated national Alzheimer’s disease research center has become a leading resource in dementia research.

Read Banking on the Brain

Paul’s Story

“Whatever was going on in the brain was hidden to the rest of us,”  said Paul’s wife, Michelle. “It is a bit of resolution, and this is the only way to get it,” she added. “It is a conclusive way to know what happened in some form because we do not know why it happened, but [now] we know what happened.”

Read Paul’s story

Featured on Texas Public Radio

“Neurodegenerative disorders can be really tricky, and even with really great clinical care, there can be little hidden things that we find in the brain and mixed features of different neurodegenerative diseases. So pathology is kind of the baseline truth, the definitive way to detect and diagnose diseases,” said Kevin Bieniek, PhD, director of the Brain Bank.

Listen to the episode