Clinical Researchers

Jamie Walker, MD, PhD

Studies focus on dementia and successful aging. “Successful agers” are resistant or resilient to the Alzheimer-type neuropathologic changes that develop in many people as they age. Understanding the process of resistance or resilience to these neuropathologic changes in successful agers will bring insight into mechanisms of prevention and ideally lead o the development of therapeutic interventions for dementia.

Hector Treviño, MPH

Hector Treviño manages epidemiologic research studies in Alzheimer’s disease that identify genetic, environmental, social-behavioral, vascular and metabolic factors and their pathways to dementia pathogenesis using observational study designs and innovative analytic techniques from biostatistics and computational biology. He also manages a double-blind, randomized controlled trial that aims to evaluate the efficacy and safety of DBS-f stimulation to slow the cognitive and functional progression of Alzheimer’s disease.

A. Campbell Sullivan, PSYD, ABPP-CN

Sudha Seshadri, MD

Sudha Seshadri, MD, is a behavioral neurologist and the Robert R. Barker Distinguished University Professor of Neurology, Psychiatry and Cellular and Integrative Physiology at the Joe R. and Teresa Lozano Long School of Medicine at the University of Texas Health Sciences Center at San Antonio. Since December 2017, she has served as the founding director of the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases which was awarded a National Institute on Aging designated Alzheimer’s Disease Research Center in 2021. The Biggs Institute combines comprehensive, compassionate, continuing clinical care for a broad range of vascular and neurodegenerative diseases with basic, computational and epidemiological research, community outreach, advocacy, training and education. The institute has a special emphasis on bringing the most advanced precision prevention, diagnosis and treatment approaches to the underserved Hispanic communities in South Texas.

Dr. Seshadri completed her medical education and residency training in Internal Medicine and Neurology at the Christian Medical College, Vellore, the Madras Medical College, Chennai and at the All India Institute of Medical Sciences in New Delhi. She later completed a second residency at Boston University, along with fellowship training in the Neurobiology of Aging and in Neuroepidemiology at the University of Massachusetts Medical Center in Worcester, Massachusetts and the National Heart, Lung, and Blood Institute Framingham Heart Study where she remains a senior investigator, with an adjunct appointment as professor of neurology at Boston University.

Her research interests are in uncovering the biology of Alzheimer’s and related dementias, stroke and vascular brain injury through epidemiological, genetic, multi-omic and biomarker studies on large, population-based cohorts. In parallel, she continues to see patients and lead clinical trials of promising therapies. She has over $95 million in grant funding from the National Institutes on Health (NIH), over 500 peer-reviewed publications, mentored over 45 physicians and scientists and won awards as a teacher, clinician and researcher, including election to Alpha Omega Alpha and the Association of American Physicians. Dr. Seshadri has lectured extensively, nationally and internationally and leads several national and international consortia. She is a recognized thought leader in Alzheimer’s and has been featured over 150 times in public media. Her goal is to leave a legacy of some effective preventive or therapeutic interventions for dementia, and a cadre of dedicated and caring clinicians and scientists whom she has helped empower.